
Dr Jacky Hattingh, Doctor of Natural Medicine | 083 650 2052
~ What the CARIBS Trial Reveals~
By Dr Jacky Hattingh
If you suffer from bloating, abdominal discomfort, constipation, diarrhea or both, as well as anxiety or depression, you may very well be diagnosed with IBS. In South Africa, Irritable Bowel Syndrome (IBS) affects an estimated 8% of the population, which translates to approximately 4.6 million people. It is more common among women and affects mainly individuals under the age of 50.
80% of IBS patients suffers from anxiety or depression, highlighting the gut-brain connection.
Gut-Brain Axis & Lifestyle Factors
South African studies echo international findings that stress, diet, and microbiome imbalances are key contributors. Urbanization, dietary shifts, and antibiotic overuse may also be influencing rising rates of IBS in developing regions.
IBS
Irritable Bowel Syndrome (IBS) can be a frustrating mystery—bloating, pain, erratic bowel habits—all with no obvious cause. But a major 2024 study published in The Lancet Gastroenterology & Hepatology suggests that what’s on your plate might offer more relief than what’s in your pillbox.
The CARIBS Trial at a Glance
Researchers from Sahlgrenska University Hospital in Sweden conducted a randomized controlled trial comparing three approaches for moderate-to-severe IBS:
LFTD Diet: A combo of Low FODMAP + traditional dietary advice. FODMAP stands for fermentable oligosaccharides, disaccharides, monosaccharides and polyols, which are short-chain carbohydrates (sugars) that the small intestine absorbs poorly.
Low-Carb Diet: Fibre-focused, low-carb, high-protein/fat.
Pharmacological Treatment: Customized medications based on the type of IBS.
After just 4 weeks, the results were striking:
76% of people on the LFTD diet saw major symptom relief
71% improved on the low-carb diet
Only 58% responded to medications
The difference was statistically significant, showing food-focused interventions aren’t just placebo—they’re potent and practical.
Why This Matters
This study offers robust evidence that dietary strategies could be considered as first-line treatment in IBS. While medications still have their place, many patients are hungry for holistic, non-pharmacologic options that restore gut harmony.
A Holistic Perspective
This aligns beautifully with naturopathic principles: healing starts in the gut, and food is not just fuel—it’s information and medicine. The blend of the Low FODMAP approach with traditional wisdom acknowledges that modern science and ancestral insight aren’t mutually exclusive—they’re synergistic.
“Let food be thy medicine and medicine be thy food” – Hippocrates
Takeaways for Practice
Personalization is key: Not all guts are created equal—what works for one may not for another.
Simplicity wins: Dietary adherence in the trial was impressively high (~90–95%).
Future direction: More research is needed to match the right diet to the right person—but the signal is clear: food matters.
From Science to Scripture
For those of us integrating faith and wellness, read more here...
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